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scienion 16  (SCIENION)


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    SCIENION scienion 16
    Scienion 16, supplied by SCIENION, used in various techniques. Bioz Stars score: 96/100, based on 308 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/scienion 16/product/SCIENION
    Average 96 stars, based on 308 article reviews
    scienion 16 - by Bioz Stars, 2026-05
    96/100 stars

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    Image Search Results


    Schematic representation of steps followed in manufacturing and analyzing microarrays, including drug and polymer solutions preparation, pipetting into well-plate, withdrawing drug solution through the printer nozzle and then dispensing at the required amount in the desired prelocated place on the substrate followed by repeating the same process for the polymer solution to print it onto the printed drug solution droplets.

    Journal: Molecular Pharmaceutics

    Article Title: High-Throughput Microarray Approaches for Predicting the Stability of Drug–Polymer Solid Dispersions

    doi: 10.1021/acs.molpharmaceut.4c00955

    Figure Lengend Snippet: Schematic representation of steps followed in manufacturing and analyzing microarrays, including drug and polymer solutions preparation, pipetting into well-plate, withdrawing drug solution through the printer nozzle and then dispensing at the required amount in the desired prelocated place on the substrate followed by repeating the same process for the polymer solution to print it onto the printed drug solution droplets.

    Article Snippet: A miniaturized, high-throughput technique was used to print microarrays of the drug–polymer mixtures using a piezoelectric inkjet printer Sciflexarrayer S5, Scienion (inkjet printer software sciflexarrayer (Scienion A, version 2.09.002)), and 70 μm orifice nozzle type 2 coating (Scienion, Germany).

    Techniques: Polymer

    Examples of different APIs/PVPVA printed dispersions. All images are reported without a cross-polarized filter (top part of each section) and with a cross-polarized filter (bottom part). The images were arranged in ascending order according to the displayed drug–polymer ratio. The top section shows the API/polymer loading ratios with no birefringence (no crystallization monitored). In contrast, the middle section shows the API/polymer loading ratios that show the start of birefringence detection (start of crystallization), and the bottom section shows the API/polymer loading ratios that show apparent birefringence detection (crystallization). Three different ratios for API/polymer loading were displayed to compare the assessment of crystallization by POM. All images are reported after storage of the microarrays in accelerated conditions for 6 months (75% relative humidity and 40 °C in stability oven). Final mass: 1000–1100 ng.

    Journal: Molecular Pharmaceutics

    Article Title: High-Throughput Microarray Approaches for Predicting the Stability of Drug–Polymer Solid Dispersions

    doi: 10.1021/acs.molpharmaceut.4c00955

    Figure Lengend Snippet: Examples of different APIs/PVPVA printed dispersions. All images are reported without a cross-polarized filter (top part of each section) and with a cross-polarized filter (bottom part). The images were arranged in ascending order according to the displayed drug–polymer ratio. The top section shows the API/polymer loading ratios with no birefringence (no crystallization monitored). In contrast, the middle section shows the API/polymer loading ratios that show the start of birefringence detection (start of crystallization), and the bottom section shows the API/polymer loading ratios that show apparent birefringence detection (crystallization). Three different ratios for API/polymer loading were displayed to compare the assessment of crystallization by POM. All images are reported after storage of the microarrays in accelerated conditions for 6 months (75% relative humidity and 40 °C in stability oven). Final mass: 1000–1100 ng.

    Article Snippet: A miniaturized, high-throughput technique was used to print microarrays of the drug–polymer mixtures using a piezoelectric inkjet printer Sciflexarrayer S5, Scienion (inkjet printer software sciflexarrayer (Scienion A, version 2.09.002)), and 70 μm orifice nozzle type 2 coating (Scienion, Germany).

    Techniques: Polymer, Crystallization Assay